SERVICES

Assessment of the Efficacy IN VITRO/INSTRUMENTAL

After evaluating the in vitro safety assessment of a product, you can proceed to verify the cosmetic properties claimed by the product itself. To this purpose, experimental protocols on cell cultures are performed in order to verify a particular action of the product when applied to a specific part of the skin. This sort of tests are carried out by high-skilled professionals in specialized laboratories and university institutes.

COMBNESS AND HAIR BREAKAGE

The aim of this test is to evaluate if the investigated product improves combness and strengthening of hair (breakage load), through an instrumental analysis carried out using a dynamometer on locks of hair treated with the investigated product.

EVALUATION OF GROWTH STIMULATING ACTIVITY WITH IN VITRO ASSAYS ON CELL CULTURES OF FIBROBLASTS AND KERATINOCYTES

The aim of this test is to evaluate the ability of a cosmetic product to stimulate fibroblast/keratinocyte cell regeneration.

EVALUATION OF THE ANTI-INFLAMMATORY ACTION (IL8)

The aim of this test is to evaluate the anti-inflammatory action of a product through the analysis of the cytokine synthesis in human fibroblast cultures treated with the investigated substance.

EVALUATION OF THE ANTI-INFLAMMATORY ACTION (IL6)

The aim of this test is to evaluate the anti-inflammatory action of a product through the analysis of the cytokine synthesis in human fibroblast cultures treated with the investigated substance.

ANTI-AGE TEST- EVALUATION OF THE ANTIOXIDANT ACTIVITY

The aim of this test is to evaluate if the tested product, at different concentrations, has an in vitro antioxidant activity on human keratinocytes. To this purpose it is tested its capability of reducing the development of reactive oxygen species (ROS). This capability should be used to neutralize the skin ageing action.

EVALUATION OF THE LIPO REDUCING ACTIVITY

The aim of the test is to determine the lipo reducing action of a cosmetic product through both a volumetric evaluation and by measuring the variation of accumulated triglycerides from adipocytes.

Instrumental evaluation of the adhesiviness of plasters

The test allows to evaluate the adhesivity of patches by measuring the force (N/cm2), through Dynamometer, needed for the detachment of the same from a smooth surface.

Instrumental evaluation of the sliding action of syringes

To evaluate the smoothness of the plunger into the syringes are carried out tests making use of the dynamometer .

EVALUATION OF THE PERCUTANEOUS ABSORPTION

The aim of this test is to define the cutaneous and transcutaneous permeation kinetics (stratum corneum, viable epidermis and derma) of the active substances by using the Franz cell on isolated skin.

EVALUATION OF THE VOLUMIZING ACTION

The aim of the test is to evaluate the volumizing power of a cosmetic product through both a volumetric evaluation and by measuring the variation of accumulated triglycerides from adipocytes.

Dermo-cosmetic and medical R&D center